5-[(S)-2,2-Dimethyltetrahydro-2H-pyran-4-yl]-1-[(1S,2S)-2-methyl-1-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)cyclopropyl]-1H-indole-2-carboxylic Acid [CAS 2212021-83-3]

5-[(S)-2,2-Dimethyltetrahydro-2H-pyran-4-yl]-1-[(1S,2S)-2-methyl-1-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)cyclopropyl]-1H-indole-2-carboxylic acid, abbreviated DTIOC (CAS 2212021-83-3), is a high-value chiral pharmaceutical intermediate — with fixed (S)- and (1S,2S)-configured stereocenters and an indole/oxadiazole scaffold — used as a key building block in the synthesis of Orforglipron, an investigational oral small-molecule GLP-1 receptor agonist. Offered by Shanghai IntVal Chemicals Co., Ltd (not the manufacturer) at HPLC purity ≥98.5% and chiral purity ≥98.0%, it is supplied for pharmaceutical R&D and intermediate synthesis only, with samples available and sales into North America, Central/South America, Asia, and the Middle East.