Education 1. Department of Pharmaceutical and Artificial-Intelligence Sciences, Institute of Medical Artificial Intelligence, Shanghai Jiao Tong University School of Medicine Shanghai, China Postdoctoral 2024.06-2026.06 2. China Pharmaceutical University & Shanghai Institute of Materia Medica, Chinese Academy of Sciences Nanjing & Shanghai, China Ph.D., Pharmaceutical Chemistry 2020.09 – 2024.09 3. Hainan University Haikou, China Master Degree., Pharmacy 2016.09 - 2019.06 Bachelor Degree., Pharmaceutical Engineering 2011.09 - 2015.09 Work Experience PHARMARON-Beijing (BDA) Pharmaceutical Co., LTD; Chemist Staff 2015.12 - 2016.09 BIOCELLS (Beijing) Biotech Co., LTD; Computer Aid Drug Design Engineer 2019.06 - 2020.07 Publications [1]Li, R., Chu, Q., He, X., Zhang, J., Cheng, X., Enhancing structure-based drug‒target interaction prediction via electron-density map-informed conformation optimization, Acta Pharmaceutica Sinica B, 2026 (Accept). [2] Li, R., Long, L., Zhu, R., Wu, C., Zhang, J. Current Status and Prospects of Combination Drug and Its Artificial Intelligence Algorithm Development. Bulletin of National Natural Science Foundation of China, 2026, 40 (2), 228-238. [3] Li, R., He, X., Wu, C., Li, M., Zhang, J. Advances in structure-based allosteric drug design. Current Opinion in Structural Biology, 2025, 90. [4] Li R, He X, Long L, Zhang J*. Research progress on design and discovery of allosteric drugs. Scientia Sinica Chimica. 2025, 55(8): 2286–2295. [5] Long, L., Li, R., Zhang, J. Artificial Intelligence in Retrosynthesis Prediction and its Applications in Medicinal Chemistry. Journal of Medicinal Chemistry, 2025, 68 (3), 2333-2355. [6]. Li, R., Chen, L., He, X., Cao, D., Zhang, Z., Jiang, H., Chen, K., Cheng, X., Loops Mediate Agonist-Induced Activation of the Stimulator of Interferon Genes Protein. Journal of Chemical Information and Modeling, 2023. Front Cover [7]. Shan B△, Hou H△, Zhang K△, Li, R.△, Shen C, Chen Z, Xu P, Cui R, Su Z, Zhang C, Yang R, Zhou G, Liu Y, Guo H, Chen K, Fu W, Jiang H, Zhang S, Zheng M. Design, Synthesis, and Biological Evaluation of Bipyridazine Derivatives as Stimulator of Interferon Genes (STING) Receptor Agonists. Journal of Medicinal Chemistry, 2023 Mar 9;66(5):3327-3347. [8]. Li, R., Li, H., and Chen, W., Silico analysis of interaction between full-length SARS-CoV2 S protein with human Ace2 receptor: Modelling, docking, MD simulation. Biophysical Chemistry, 2020. 267. Research Grants [1]Innovative Drug Research and Development National Science and Technology Major Project (2025ZD1803100) /2025.12-2028.11/87, 480,000, Co-Investigator National Natural Science Foundation of China (82441035) /2025.1-2027.12/2,600,000, Co-Investigator