CAS Number: 79517-01-4
EC Number: 616-695-4
Molecular Weight: 1139.3
Chemical Formula: C₅₃H₇₄N₁₀O₁₄S₂
IUPAC Name: acetic acid;(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-19-[[(2R)-2-amino-3-phenylpropanoyl]amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-[(1R)-1-hydroxyethyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosa
Valoración (Assay): Valoración (HPLC): 95.0–102.0% de octreotide acetate sobre base anhidra/seca, conforme al límite de la monografía farmacopeica aplicable.
Purity: Pureza ≥ 98.0% mediante normalización de áreas por HPLC, confirmada con certificado de análisis para cada lote de producción.
Perfil de impurezas: Impurezas individuales no especificadas ≤ 0,10 % e impurezas totales ≤ 0,5 %, for indications spanning acromegaly, carcinoid syndrome and VIPomas, controladas mediante métodos HPLC/UPLC validados.

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Descripción adicional:

This synthetic octapeptide analogue of naturally occurring somatostatin (CAS 83150-76-9; molecular formula C49H66N10O10S2; molar mass 1019.26 g/mol; sequence H-D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys-L-threoninol acetate salt with a disulfide bond) has a longer duration of action than somatostatin itself and is used for acromegaly, carcinoid syndrome and VIPomas. Octreotide acetate suppresses secretion of gastro-entero-pancreatic peptide hormones and growth hormone release, while also slowing gastrointestinal motility and inhibiting gallbladder contraction.