CAS Number: 851199-59-2
EC Number: 812-291-9
Molecular Weight: 1526.8
Chemical Formula: C₅₉H₇₉N₁₅O₂₁S₆
IUPAC Name: (2S)-2-[[(1R,4S,7S,13S,16R,21R,24R,27S,30S,33R,38R,44S)-21-amino-13-(2-amino-2-oxoethyl)-27-(2-carboxyethyl)-44-[(1R)-1-hydroxyethyl]-30-[(4-hydroxyphenyl)methyl]-4-methyl-3,6,12,15,22,25,28,31,40,43,46,51-dodecaoxo-18,19,35,36,48,49-hexathia-2,5,11,14,23
Valoración (Assay): Pureza ≥98 % por HPLC
Purity: Péptido sintético de 14 aminoácidos (C59H79N15O21S6, PM 1526,74 g/mol) ciclado mediante tres puentes disulfuro
Perfil de impurezas: Total de sustancias relacionadas/impurezas ≤0,5 %, controlado mediante métodos analíticos validados

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Descripción adicional:

Linaclotide (CAS 851199-59-2) has the sequence H-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH, cyclized via three disulfide bonds (1-6, 2-10, 5-13), molecular formula C59H79N15O21S6, molar mass 1526.74 g/mol, purity ≥98%, impurity ≤0.5%, requiring storage at 2-8°C and packed in 1 g, 10 g, or 50 g bottles or per customer requirement. It is approved for treating constipation-predominant irritable bowel syndrome and chronic idiopathic constipation in adults.