EC Number: 435-850-5
CAS Number: 135635-46-0
IUPAC Name: (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-17-ethyl-1,14-dihydroxy-12-[(E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone
Application: Immunomodulateur (de type tacrolimus) pour la dermatite atopique, le psoriasis, la GVHD et autres maladies cutanées auto-immunes
Molecular Weight: 792
Chemical Formula: C₄₃H₆₉NO₁₂
Statut réglementaire: Qualité pharmaceutique

Autres informations

Description supplémentaire:

Ascomycin is a tacrolimus-related macrolide immunosuppressant, manufactured directly by Beijing Global Biologicals Co., Ltd to pharmaceutical grade. It is used in the treatment of autoimmune and inflammatory skin conditions including atopic dermatitis, allergic contact dermatitis, psoriasis, lupus erythematosus, lichen planus, vitiligo, Netherton syndrome, and graft-versus-host disease (GVHD), and is distributed across Asia and Africa. The CAS number recorded for this listing (11011-38-4) differs from ascomycin's commonly referenced CAS of 104987-12-4, so the exact compound identity should be verified with the supplier.