CAS Number: 851199-59-2
EC Number: 812-291-9
Molecular Weight: 1526.8
Chemical Formula: C₅₉H₇₉N₁₅O₂₁S₆
IUPAC Name: (2S)-2-[[(1R,4S,7S,13S,16R,21R,24R,27S,30S,33R,38R,44S)-21-amino-13-(2-amino-2-oxoethyl)-27-(2-carboxyethyl)-44-[(1R)-1-hydroxyethyl]-30-[(4-hydroxyphenyl)methyl]-4-methyl-3,6,12,15,22,25,28,31,40,43,46,51-dodecaoxo-18,19,35,36,48,49-hexathia-2,5,11,14,23
Titre (Assay): Pureté ≥98 % par HPLC
Purity: Peptide synthétique de 14 acides aminés (C59H79N15O21S6, MM 1526,74 g/mol) cyclisé via trois ponts disulfures
Profil d'impuretés: Total des substances apparentées/impuretés ≤0,5 %, contrôlé par des méthodes analytiques validées

Autres informations

Description supplémentaire:

Linaclotide (CAS 851199-59-2) has the sequence H-Cys-Cys-Glu-Tyr-Cys-Cys-Asn-Pro-Ala-Cys-Thr-Gly-Cys-Tyr-OH, cyclized via three disulfide bonds (1-6, 2-10, 5-13), molecular formula C59H79N15O21S6, molar mass 1526.74 g/mol, purity ≥98%, impurity ≤0.5%, requiring storage at 2-8°C and packed in 1 g, 10 g, or 50 g bottles or per customer requirement. It is approved for treating constipation-predominant irritable bowel syndrome and chronic idiopathic constipation in adults.