American pharmaceutical company formed in 1982 when SmithKline Corporation of Philadelphia merged with Beckman Instruments, best known for the ulcer medicine cimetidine sold as Tagamet, which passed into SmithKline Beecham in 1989 and then into GlaxoSmithKline in 2000. Made and sold prescription medicines, vaccines and consumer health products and ran clinical laboratory and analytical instrument businesses alongside its own research laboratories and manufacturing.
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