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AA

メンバー概要

自己紹介

• As a synthetic and medicinal chemist, my research focus centers around the design and synthesis of biologically active compounds, particularly small molecules for drug discovery purposes. My main interest lies in developing agents with anti-cancer properties, specifically those that bind stoichiometrically to tubulin, alter its conformation, and arrest mammalian cells at mitosis without causing gross deformations of cellular microtubules. I also have a strong background in working with Active Pharmaceutical Ingredients (APIs). • In terms of practical skills, I have extensive hands-on experience in conducting multistep syntheses and performing bench-scale synthesis of various medicinal compounds ranging from milligrams to grams. I am well-versed in purifying compounds using chromatography techniques and characterizing them through methods such as LCMS (Liquid Chromatography-Mass Spectrometry), HPLC (High-Performance Liquid Chromatography), and NMR spectroscopy. • I am proficient in conducting literature searches in chemistry journals and other relevant sources using platforms like Google Scholar, SCI-Finder, Sci-Hub, PubMed, Reaxys, among others. This allows me to stay up-to-date with the latest advancements in the field. • Additionally, I possess expertise in performing in silico analysis of compounds through molecular docking methods. By utilizing drug design software such as Schrödinger and AutoDock, I can comprehend their binding modes with the target molecule. Furthermore, my familiarity with Design of Experiment software enables me to optimize reaction conditions for improved efficiency.

学歴

  • Shahid Beheshti University
    学位 Master of Science
    専攻 Medicinal Chemistry
    開始日 01/2021
    終了日 01/2024
  • Shahid Beheshti University
    学位 Bachelor of science
    専攻 Chemistry
    開始日 01/2017
    終了日 01/2021