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Staff Scientist

Dr. RAMKUMAR MODUKURI

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職務要約

I am Ramkumar Modukuri, presently I am working as post-doctoral position in department of Medicinal Chemistry at California Institute For Biomedical Research (Calibr), San Diego. I have completed my Ph.D. in field of Synthetic and Medicinal Chemistry from CSIR- Central Drug Research Institute, Lucknow-India. Currently in my post doctorate, I am working to ‘‘Host-targeted therapies for Diarrheal disease: Novel approaches to identifying anti-cryptosporidium drugs’’. I am also engaged in different projects in present institute. During my Ph.D. research, I have gained experience in Medicinal Chemistry, During in my research, I have designed and synthesized medicinally active different types of oxygen heterocycles as privileged structures to evaluate their various pharmaceutical properties like anti-alzheimer’s, anti-parkinson’s, anti-depressant, anti-osteoporotic, anti-malarial and anti-filarial activities. In this process, I have synthesized a large number of different heterocyclic compounds of pharmacological interest. More interestingly, I have designed different chemical entities in which can interact with particular cite of action. I have experience in designing and synthesis of medicinally active hit to lead optimization of lead active scaffolds. My research work has been published in international journals of repute 15 International papers, details of which are being attached with the CV. My citations indices are available at http://scholar.google.co.in/citations?user=aoEPqxAAA AAJ&hl=en The research work has been published through peer reviewed publications. Two of my works have accepted as a front cover art in ACS Medicinal Chemistry Letters (2014 & 2015).

スキル

Medicinal Chemistry
Organic chemistry
Drug Development and Industrial Pharmacy
Drug Discovery
Pharmacophore
Scaffold
Hit to lead
SAR
Structure activity relationship
lead optimization
disease
parasite
activity
invention
Drug
Drug Design
drug molecule
therapeutic targets
target
Hybrids
Inhibitors
agonist
antagonist
derivatives
receptors
ligands
Synthesis

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