>25y experienced safety pharmacologist and translational scientist specialized in mechanistic predictive safety and secondary pharmacology. My work focuses on advancing early, mechanism-based safety strategies by integrating in vitro pharmacology, exposure data, and AI-enabled interpretation to improve decision-making in drug discovery. I actively contribute to cross-industry initiatives (IQ Consortium, Pistoia Alliance) to shape standardized, regulator-ready safety frameworks and promote the adoption of predictive, human-relevant approaches aligned with evolving regulatory expectations.