IUPAC Name: (3aS)-1-methyl-3,3-diphenyl-3a,4,5,6-tetrahydropyrrolo[1,2-c][1,3,2]oxazaborole
EC Number: 601-150-5
Molecular Weight: 277.2
Chemical Formula: C₁₈H₂₀BNO
CAS Number: 112022-81-8

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(S)-(-)-2-Methyl-CBS-oxazaborolidine (CAS 112022-81-8) is a chiral oxazaborolidine catalyst used with borane to achieve highly enantioselective reductions of ketones, including acetophenone-type substrates, in the synthesis of optically active pharmaceutical intermediates. It is applied in the production of beta-adrenergic agonist drugs such as dobutamine, isoprenaline, salmeterol, and formoterol, offering good stereoselectivity and easy product separation. It is supplied by Shanghai Forxine Pharmaceutical Co., Ltd. and distributed to markets across the Americas, Europe, and Asia.