CAS Number: 128270-60-0
EC Number: 811-536-7
Molecular Weight: 2180.3
Chemical Formula: C₉₈H₁₃₈N₂₄O₃₃
IUPAC Name: (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-4-amino-2-[[2-[[2-[[2-[[2-[[(2S)-1-[(2S)-2-[[(2S)-1-[(2R)-2-amino-3-phenylpropanoyl]pyrrolidine-2-carbonyl]amino]-5-carbamimidamidopentanoyl]pyrrolidine-2
Purity: HPLC 기준 98.0% 이상, 전형적인 의약품/원료의약품 등급 규격
Melting Point: 해당 물질의 약전 모노그래프 기준 참조 융점 범위에 부합
불순물 프로파일: 유연물질/불순물은 ICH Q3A에 따라 밸리데이션된 규격 한도 내로 관리

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Used as an anticoagulant in patients with unstable angina undergoing percutaneous transluminal coronary angioplasty, bivalirudin is a synthetic 20-residue peptide that reversibly inhibits thrombin; once bound to the active site, thrombin can no longer convert fibrinogen to fibrin, the key step in thrombus formation. It is given intravenously, and because it can cause blood stagnation, monitoring hematocrit, activated partial thromboplastin time, international normalized ratio, and blood pressure is important.