CAS Number: 851199-59-2
Chemical Formula: C₅₉H₇₉N₁₅O₂₁S₆
적응증: 변비형 IBS 및 만성특발성변비 치료용 합성 14아미노산 구아닐산고리화효소-C(GC-C) 작용제
IUPAC Name: (2S)-2-[[(1R,4S,7S,13S,16R,21R,24R,27S,30S,33R,38R,44S)-21-amino-13-(2-amino-2-oxoethyl)-27-(2-carboxyethyl)-44-[(1R)-1-hydroxyethyl]-30-[(4-hydroxyphenyl)methyl]-4-methyl-3,6,12,15,22,25,28,31,40,43,46,51-dodecaoxo-18,19,35,36,48,49-hexathia-2,5,11,14,23
EC Number: 812-291-9
Molecular Weight: 1526.8
저장 조건: 2-8°C 냉장 보관, 차광, 냉동 금지
규제 승인 상태: 성인 IBS-C 및 만성특발성변비 치료에 대해 FDA 승인

기타 정보

추가 설명:

Linaclotide is a synthetic 14-amino-acid peptide related to the endogenous guanylin peptide family, and is the only FDA-approved, clinically available locally acting intestinal GC-C (guanylate cyclase-C) agonist for treating constipation-predominant IBS and chronic idiopathic constipation in adults.