전문 요약
• At Amgen, I serve as Clinical Pharmacology TA Head for Hematology Oncology (Liquid/Solid Tumors) TA & for Rare Disease TA & provide strategic & scientific leadership to Global Clinical Pharmacology Leads (team of direct reports including Directors, Associate Directors, Senior Principal Scientists) responsible for providing Clinical Pharmacology, Modeling and Simulation leadership to the global drug development teams for Hematology Oncology TA & Rare Disease TA. I also head a group of experts as direct reports in Mechanistic-PBPK Modeling & Simulation. I also serve on the Amgen, San Francisco site leadership as co-chair of Extended Leadership Team.
• I have 2 decades of industry new drug development clinical pharmacology & pharmacometrics experience for both small molecule drugs & therapeutic proteins/innovative novel modalities across TAs of oncology, rare diseases, inflammation, & CV/Met from Amgen, Bristol-Myers Squibb, & Dr. Reddy's Laboratories. I have significant contributions to global filings & approvals of several marketed small molecule & therapeutic protein drugs across TAs including Saxagliptin (ONGLYZA®), Saxagliptin & Metformin IR & XR (KOMBOGLYZE® & KOMBIGLYZE XR®), Apixaban (ELIQUIS®), Carfilzomib (KYPROLIS®), & Blinatumomab (BLINCYTO®).
• I received training as a pharmacist & earned my PhD from the University of Maryland in Pharmacokinetics/Pharmacodynamics & Biopharmaceutics. I serve as Associate Editor for the journal Clinical Pharmacology in Drug Development (CPDD) & on the Editorial Boards of the journal Clinical Pharmacology & Therapeutics (CPT), the Journal of Clinical Pharmacology (JCP), & the journal Clinical Pharmacokinetics (Clin Pharmacokin). I am a Board Member & elected Regent of the American College of Clinical Pharmacology & a Fellow of the American College of Clinical Pharmacology (FCP). I am IQ Consortium Clinical Pharmacology Leadership Group Amgen representative & also serve as an Affiliate Assistant Professor at the University of Maryland School of Pharmacy & Industry Advisory Board Member of the Washington State University, College of Pharmacy Pharmaceutical Sciences. I have authored 50+ peer-reviewed scientific journal article publications in the field of clinical pharmacology & pharmacometrics.
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