Ascomycin
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Product Name
Ascomycin
Details
Substance
Manufacturer(s)
Specifications
- EC Number: 435-850-5
- CAS Number: 135635-46-0
- IUPAC Name: (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-17-ethyl-1,14-dihydroxy-12-[(E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone
- Application: Immunomodulator (tacrolimus-like) for atopic dermatitis, psoriasis, GVHD & other autoimmune skin diseases
- Molecular Weight: 792
- Chemical Formula: C43H69NO12
- Regulatory Status: Pharmaceutical grade
Other Information
Additional Description:
Ascomycin is a tacrolimus-related macrolide immunosuppressant, manufactured directly by Beijing Global Biologicals Co., Ltd to pharmaceutical grade. It is used in the treatment of autoimmune and inflammatory skin conditions including atopic dermatitis, allergic contact dermatitis, psoriasis, lupus erythematosus, lichen planus, vitiligo, Netherton syndrome, and graft-versus-host disease (GVHD), and is distributed across Asia and Africa. The CAS number recorded for this listing (11011-38-4) differs from ascomycin's commonly referenced CAS of 104987-12-4, so the exact compound identity should be verified with the supplier.
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