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Sichuan Qingmu Pharmaceutical Co., Ltd sell "Dabigatran Etexilate Mesylate"

Basic Information

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Trade Type

Sell

Product Name

Dabigatran Etexilate Mesylate

Specifications

  • EC Number: 828-727-6
  • Chemical Formula: C35H45N7O8S
  • CAS Number: 872728-81-9
  • IUPAC Name: ethyl 3-[[2-[[4-(N-hexoxycarbonylcarbamimidoyl)anilino]methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoate;methanesulfonic acid
  • Molecular Weight: 723.8
  • Assay: Complies with the assay requirements of the applicable pharmacopoeial monograph (USP/EP/BP), typically ≥98.0%.
  • Impurity Profile: Related substances and impurities controlled within ICH Q3A/Q3B limits using validated HPLC methods.

Other Information

Additional Description:

Dabigatran, marketed under brand names including Pradaxa, is an anticoagulant used to treat and prevent blood clots and to prevent stroke in patients with atrial fibrillation, including prevention of clots after hip or knee replacement and in those with a history of previous clots. It serves as an alternative to warfarin that does not require routine blood monitoring. A meta-analysis of seven studies found no added benefit over warfarin in preventing ischemic stroke, though dabigatran carried a lower risk of intracranial bleeding and a higher risk of gastrointestinal bleeding compared with warfarin. It is administered orally, with bleeding and gastritis among the common side effects, and other possible effects including bleeding around the spine.
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