Shanghai Haoyuan ChemExpress Co., Ltd. sell "MMAE"
Shanghai Haoyuan ChemExpress Co., Ltd.
Basic Information
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Product Name
MMAE
Substance
Manufacturer(s)
Specifications
- EC Number: 811-424-8
- CAS Number: 474645-27-7
- IUPAC Name: (2S)-N-[(2S)-1-[[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-3-[[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]-3-methyl-2-(methylamino)butanamide
- Application: Cytotoxic payload conjugated to monoclonal antibodies to form antibody-drug conjugates (ADCs) for cancer therapy; too toxic for standalone administration.
- Molecular Weight: 718
- Chemical Formula: C39H67N5O7
- Purity: Synthetic derivative of dolastatin 10 (CAS 474645-27-7), manufactured to high purity suitable for ADC conjugation chemistry.
Documents
FDAGMPISO
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