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Sell

Service Name

TIM Cell

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Specifications

  • Country of Origin: Netherlands
  • Certification Standard: Manufactured under GMP/ISO 9001 quality system; audited facility
  • Application: Caco-2 dynamic-flow, organ-on-a-chip system combined with TIM gastrointestinal effluents to assess intestinal permeability (apparent permeability, Papp) and predict oral drug absorption

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Additional Description:

TIM Cell is an organ-on-a-chip system incorporating Caco-2 cells to assess intestinal permeability under physiologically relevant conditions, using fed or fasted TIM effluents to evaluate how well active pharmaceutical ingredients cross the intestinal barrier. It is commonly applied to forecast oral drug absorption, helping confirm or narrow down candidate selection early enough to avoid costly late-stage development setbacks.
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