Abemaciclib

Specifications

1231929-97-7CAS Number

806-670-8EC Number

N-[5-[(4-ethylpiperazin-1-yl)methyl]-2-pyridinyl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amineIUPAC Name

C27H32F2N8Chemical Formula

506.6 g/molMolecular Weight

Abemaciclib; 1231929-97-7; LY2835219; Verzenio; LY-2835219; N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine; Verzenios; 60UAB198HK; N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine; LY 2835219; LY2835210; LY-2835210; 2-Pyrimidinamine, N-(5-((4-ethyl-1-piperazinyl)methyl)-2-pyridinyl)-5-fluoro-4-(4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl); 5-(4-ethylpiperazin-1-ylmethyl)pyridin-2-yl)-(5-fluoro-4-(7-fluoro-3-isopropyl-2-methyl-3H-benzimidazol-5-yl)pyrimidin-2-yl)amine; 5-(4-ethylpiperazin-1-ylmethyl)pyridin-2-yl)-(5-fluoro-4-(7-fluoro-3-isopropyl-2-methyl-3H-benzoimidazol-5-yl)pyrimidin-2-yl)amine; N-{5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-[4-fluoro-2-methyl-1-(propan-2-yl)-1H-1,3-benzodiazol-6-yl]pyrimidin-2-amine; abemaciclibum; N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo(d)imidazol-6-yl)pyrimidin-2-amine; N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-2-methyl-1-(propan-2-yl)-1H-1,3-benzodiazol-6-yl)pyrimidin-2-amine; N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine; RefChem:58097; L01XE50; LY2385219; 806-670-8; LY2835219 free base; MFCD22665744; 2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-; C27H32F2N8; Abemaciclib (ly2835219); HY-16297A; s5716; CS-1230; N-[5-[(4-Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine; UNII-60UAB198HK; N-{5-[(4-Ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-[4-fluoro-2-methyl-1-(propan-2-yl)-1H-benzimidazol-6-yl]pyrimidin-2-amine; Abemaciclib [USAN:INN]; Abemaciclib,LY2835219; rimidin-2-amine; Verzenio (TN); 6ZV; N-{5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-[4-fluoro-2-methyl-1-(propan-2-yl)-1H-benzimidazol-6-yl]py rimidin-2-amine; Abemaciclib (Standard); CDK4/6 dual inhibitor; ABEMACICLIB [MI]; ABEMACICLIB [INN]; ABEMACICLIB [JAN]; ABEMACICLIB [USAN]; ABEMACICLIB [WHO-DD]; Abemaciclib (JAN/USAN/INN); GTPL7382; orb1305567; orb3141360; SCHEMBL2487229; CHEMBL3301610; SCHEMBL29356350; SCHEMBL29423472; SCHEMBL29591527; ABEMACICLIB [ORANGE BOOK]; DTXSID20673119; EX-A521; CHEBI:233362; UZWDCWONPYILKI-UHFFFAOYSA-N; GLXC-90338; HMS3673I05; HMS5085C17; HY-16297AR; EX-A1588; BDBM50110183; EBC-17139; NSC768073; NSC783671; AKOS025404907; LY2835219 free base (Abemaciclib); CCG-269750; DB12001; LY-28352192-PYRIMIDINAMINE; NSC-768073; NSC-783671; SB16476; LY2835219 free base (Abemaciclib)?; NCGC00351599-02; NCGC00351599-06; NCGC00351599-10; AC-30666; AS-10230; BP-43621; DA-33422; FE103812; LY2835219 Ms salt, Abemaciclib Ms salt; LY 2835210; NS00072970; D10688; EN300-7406007; A044176; F979456; BRD-K33622447-066-01-9; Q23901483; [5-(4-ethyl-piperazin-1-ylmethyl)-pyridin-2-yl]-[5-fluoro-4-(7-fluoro-3-isopropyl-2-methyl-3H-benzoimidazol-5-yl)-pyrimidin-2-yl]-amine; Ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-2-pyrimidinamine; N-[5-[(4-ETHYL-1-PIPERAZINYL)METHYL]-2-PYRIDINYL]-5-FLUORO-4-[4-FLUORO-2-METHYL-1-(1-METHYLETHYL)-1H-BENZIMIDAZOL-6-YL]-; N-[5-[(4-ethylpiperazin-1-yl)methyl]-2-pyridyl]-5-fluoro-4-(7-fluoro-3-isopropyl-2-methyl-benzimidazol-5-yl)pyrimidin-2-amine; N-{5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-(7-fluoro-3-isopropyl-2-methyl-1,3-benzodiazol-5-yl)pyrimidin-2-amine; N-{5-[(4-Ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-[4-fluoro-2-methyl-1-(propan-2-yl)-1H-1,3-benzimidazol-6-yl]pyrimidin-2-amine; N-{5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-[4-fluoro-2-methyl-1-(propan-2-yl)-1H-benzimidazol-6-yl]pySynonyms