Before I came to the US, I was trained as a biological and pharmaceutical researcher with the background in health science, pharmacy, chemistry and biology in the combined bachelor’s/master’s program. I had research background of both in vitro cell models and in vivo animal models (including mouse, rat, rabbit, and zebrafish). My research goal was to build up a simple animal model to predict preclinical toxicity of chemicals. We used rat model to test the neurotoxicity caused by alumina oxide nanoparticles, and prenatal exposed rats to study the toxicity of PFOS. I also helped to establish methods using the probe modified gold nanoparticles and to measure chemical pollutants and microRNA from environmental and cell culture samples. I came to US with an interest in toxicology. Toxicology is the practical science with the multifactorial and multidisciplinary nature. Toxicologists should know and apply the cutting edge technologies to study the mechanism of toxicity. However, there are still a lot of unknown aspects in toxicology. With the incredible increase of man-made chemicals, the development of toxicology currently cannot meet the requirements.