Postdoctoral Researcher

With a strong background in organic, organometallic, and bioinorganic chemistry, my research has focused on optimizing the design and synthesis of metal complexes—primarily rhodium(III) half-sandwich compounds, but also including iridium, ruthenium, and rhenium derivatives. During my PhD, I synthesized over 100 coordination compounds, many of which featured a tether between the cyclopentadienyl and Z ligands. This design element modulates the reactivity of the metal–ligand (M–Z) bond, believed to be crucial in enhancing the cytotoxicity of these complexes. The diversity of the compound library enabled an in-depth structure–activity relationship (SAR) study, particularly regarding interactions with biologically relevant substrates in bioorthogonal chemistry. I have also contributed to methodological advances such as the use of ¹⁰³Rh NMR spectroscopy to elucidate unique ¹H NMR signals in rhodium(III) tether complexes, and explored the incorporation of metal complexes into mechanically interlocked nanotubes (MINTs) for electrochemical applications. After successfully defending my PhD, I joined the group of Prof. Aidan McDonald at Trinity College Dublin, where my current postdoctoral research focuses on iron, cobalt, nickel, and copper biomimic complexes for C–H bond oxidation catalysis. I am also investigating salen-type ligand complexes of these metals for their application in CO₂ copolymerization. Previous international research stays with Prof. Claudia Turro (The Ohio State University) and Prof. Alceo Macchioni (University of Perugia) expanded my expertise to hydrogen evolution (HER) and water oxidation catalysis (WOC). These experiences demonstrate my capacity to generate and pursue original scientific hypotheses, carry out complex experimental designs, and communicate results effectively through peer-reviewed publications and international conferences. 1.2 Scientific and Technical Skills I have developed advanced synthetic and analytical skills, including: -Organic and organometallic synthesis, with experience designing efficient synthetic routes for complex molecules. -Glovebox and Schlenk line techniques for the handling and synthesis of air- and moisture-sensitive metal complexes, including catalytically active species. -Single-crystal X-ray diffraction, with 45 resolved structures enabling structure–reactivity studies. -Paramagnetic complex characterization, including spectroscopic analysis of 3d-metal species. -Photophysical studies, such as quantum yield determination of BODIPY-based complexes. -Electrochemical and photochemical techniques, developed through HER and WOC catalyst studies. -Gas chromatography and barometric measurements to assess catalytic activity. -Biological evaluations, including the development of solubility assays and cytotoxicity profiling of metal complexes. Beyond technical skills, I have led laboratory resource management, supervised experimental workflows, and ensured good scientific practice in collaborative research settings. I have successfully coordinated multidisciplinary projects, fostering productivity and effective teamwork. 1.3 International Collaborations and Leadership My active involvement in international research has included the implementation of innovative methodologies and the transfer of knowledge across institutions. I have collaborated closely with researchers abroad to achieve shared goals, showcasing leadership, adaptability, and a strong capacity for communication in multicultural scientific environments.