Dr. Honglei Zhang is currently an Associate Researcher at the School of Ethnic Medicine, Yunnan University of Traditional Chinese Medicine. He obtained his Ph.D. in Genetics from the Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences in 2013, and completed postdoctoral training at Ohio University (USA) and the Kunming Institute of Zoology. His research focuses on uncovering the molecular mechanisms of lung cancer initiation, drug resistance, and metastasis through integrative multi-omics and functional analyses. He is also engaged in natural product screening for potential therapeutic agents. Dr. Zhang has been awarded several competitive research grants, including the National Natural Science Foundation of China (General Program, Youth Program, and Regional Fund), and key projects from the Yunnan Provincial Department of Science and Technology. He has published as first or corresponding author in high-impact journals such as National Science Review, PNAS, eLife, and Cancer Letters. His recent work revealed novel proteogenomic insights into coal-smoke-associated lung cancer in Xuanwei, offering valuable directions for targeted therapy and disease prevention.