EC Number: 435-850-5
CAS Number: 135635-46-0
IUPAC Name: (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-17-ethyl-1,14-dihydroxy-12-[(E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone
用途: 免疫调节剂（类他克莫司），用于特应性皮炎、银屑病、移植物抗宿主病及其他自身免疫性皮肤病
Molecular Weight: 792
Chemical Formula: C₄₃H₆₉NO₁₂
监管状态: 药用级

其他信息

补充描述:

Ascomycin is a tacrolimus-related macrolide immunosuppressant, manufactured directly by Beijing Global Biologicals Co., Ltd to pharmaceutical grade. It is used in the treatment of autoimmune and inflammatory skin conditions including atopic dermatitis, allergic contact dermatitis, psoriasis, lupus erythematosus, lichen planus, vitiligo, Netherton syndrome, and graft-versus-host disease (GVHD), and is distributed across Asia and Africa. The CAS number recorded for this listing (11011-38-4) differs from ascomycin's commonly referenced CAS of 104987-12-4, so the exact compound identity should be verified with the supplier.

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