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HK inno.N Corporation sell "Tegoprazan"

基本信息

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子类别与细分类别

交易类型

出售

产品名称

Tegoprazan

规格参数

  • CAS Number: 942195-55-3
  • Chemical Formula: C20H19F2N3O3
  • 适应症: 通过钾离子竞争性酸阻滞剂(P-CAB)治疗酸相关性胃肠疾病,定位为质子泵抑制剂(PPI)的替代方案
  • IUPAC Name: 7-[[(4S)-5,7-difluoro-3,4-dihydro-2H-chromen-4-yl]oxy]-N,N,2-trimethyl-3H-benzimidazole-5-carboxamide
  • EC Number:
  • Molecular Weight: 387.4
  • 剂型: 配制为每日一次的口服片剂,符合典型P-CAB剂型
  • 监管批准状态: 已在韩国完成III期临床开发,并在国际范围内开展了额外的III期研究

其他信息

补充描述:

Tegoprazan is a novel, patented potassium-competitive acid blocker (P-CAB) that addresses limitations found in traditional proton pump inhibitors (PPIs) and rival P-CABs. Its advantages have been shown through Phase 3 trials in Korea and a Phase 1 trial in the US, leading to MFDS approval in 2019 across four indications: erosive reflux disease (ERD), non-erosive gastroesophageal reflux disease (NERD), gastric ulcer (GU), and Helicobacter pylori eradication. Beyond South Korea, it has gained approval in China, Mongolia, and the Philippines, among the 34 countries where HK inno.N has out-licensed it, and the company is actively seeking partners to develop Tegoprazan in unpartnered territories. Contact Ga-Young Lee (BD) at [email protected] for details.
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